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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80898d9a00ecc4aa642b55c23b03028bd53367f41fcfc0256cda08180b4b9fc9' 
  AND token = 'J2X9Y0Wx7VG18pzev445YJBLyCNIhXE/XJy9XxY/pBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}