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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2491b92e9a18274dc8afc1b2b729dd45b979e5fb115e97a9b5c2653f6755772d' 
  AND token = 'oX89E9paOzlCRp9ZPgqBeUrjY0oehkAJuNhHt2Ni2cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}