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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e614b8287369b306af3e93382e9a0f0bc8646fd5b65962cdc20257e78fba40d' 
  AND token = 'POFcSZOOsB1rXs//nWRABcsOhSegFLYV2s/xmO2LRUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}