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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '399e854aa339009c270038a4e67be56beb1eda72a8cb815e9b484dc82bce68b0' 
  AND token = 'hQw5saFkhbfE/9N3BfLYEryimZJK9kih4z5AzfurJrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}