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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8532abc863b26bef108033bc3b7f840d9f8c54c0a12f45e6029f632e251b4b2f' 
  AND token = 'u468tnNn5GDKBCQG5x84RlLu24VU4lDuR0Jo4HZXI9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}