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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f07be20c1e806c49970bf89347bc618969ae420b032a2aab12346a60d1cffa' 
  AND token = '18UJ/GDrYvGjVP+hHhN4OpnaIQXXOJUz0VjbQ3729YY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}