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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003c52b2f34ab8ee1a0d66eac370d73c0950d33f60836ad84f1b0330bf5db5f2' 
  AND token = 's4V4xicpEckN/XYdwP2UTt64wbYYykFr2M0+j46hSTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}