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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5e16a8d5c1fa072f88371183a3cbedafc09a299e3b8cf6d496bb57e75b7ac59' 
  AND token = 'KYx1cIB0QzlpOVs5Q+Mmk3qyQ0tTf2m2SelBoU/T3rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}