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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90c6a4814d951464746d78adfb15e97d2166ff104b0fc5acbc52d2c639b90f3b' 
  AND token = 'vd+/QmnpiXmMbCUYzaW26RRK5caPr5f0yXNitXGzxx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}