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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb8e8db7d9f41e80c03989014632fc5058b0676609394e4708d7171b6f03ec5' 
  AND token = '8eVbEqB/zNsqekvvvYbAB+mxcutNCUsPc7S6cI8ByZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}