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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc6ab49412601e55a3a056ccf824f20b5e76236d6962623728a15e0931c6af3' 
  AND token = 'kZL2eduLqzXpfxgCM+CUYJvzJS73OceiUKxW8ntk6y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}