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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356e84c345917ddaac584e628dc08039f2a159a5d92f8655f422889c3c4f2899' 
  AND token = 'l/1w3ud64G4kCqyW6ZYT6SsqLOSIXCYlOC2MqPasWzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}