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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321d5f55f17dfae8d38a3259e0673b79672388da7f7e694c18c6600f2fb7022e' 
  AND token = '+03FJ8e9NDKpj+PCqqW9AsSt8p4jTW/D3nkyih9Oe90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}