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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250dc570cf4cd2aecbba90f391f195e0dd0933da8c73a8848c800e9a9b32c71a' 
  AND token = '+1eAAxhfvZ5T6rfuq09gZox4m/9A+6zaYoXu2SrK8xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}