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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8c9b4a74761b3882810bc4033ce8fd761e34c3ec9d3303aac29c7e25d42a48' 
  AND token = '18xIJWJE+f9SCSp8tPJvEEedeCAIoYYH/D629ZtlJ98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}