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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1791d8e0702b7bcf0dcc0a9b579733a2a49461d7394301ad093a994904133b79' 
  AND token = '7Zbkj7aiblLT33+TS8bj6XwSuabXyzJRGnRvOZviIqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}