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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e79b3a1bdb52f7e5caa33acee9a309eb60161dcb50d9519d403a2a31aac1dd99' 
  AND token = 'EJOoU+gpG6bNk/6P3ZsErBxIAG6/cbM9NWu6mHHMZq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}