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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bab8bc51a91522d0f2eaed5e8c49c5498030a981cf98e96cd5106bbd041c81' 
  AND token = 'rJVvlwvc4drNlYKk0brCVnqT+px3UHOnZi8yUCwfLxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}