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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9c5c8ac824f8e898aa7eb655b62afbdf7b18c4d50c0b8b9837b5c35e3736ed' 
  AND token = 'JfNEPNYvSwCKO8V/sHlfx87ZjcTo4WjEUO0qTRbu7S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}