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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '706219d91106db2ab5071eedf0c03d0742eaf66e0f0a05ed3baa5a534ae5e344' 
  AND token = 'AfUk1XdfBPVjTEdD/vDCUACD6Wzvt1SvxQxQJRB4WHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}