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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7526fcab0343ccfbcb5516b0a63025d41f19424ea234dd9d2c9bd834c5c8de69' 
  AND token = 'BM9zvqVyY2+Dlxeoxf/XH7UaoDEO9FXUXbt9MqV90jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}