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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d3e3b3471ce64c39230315b04f4ed03df9a77a96ccd67055087e9ffabed243' 
  AND token = 'M54iI69AEiJzoIM03pJY6833tD0IU04IEG1ILuW3SHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}