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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9dd79925229edf8ca9c268dc57bfdbeb7b521ba38d5e0d2dd221d1c6066aba1' 
  AND token = '+1o3+Epp83jd5vKqXSsd2puqoL3hFycBloVzgfyt1+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}