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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '507a5e3e820121d94d4c18aae77f3da46f56319d9e4419e6a3e55bdd6ec37fc2' 
  AND token = 'VYxPTJsa3H6xiX8FLeIL/Nm4jvbQI/b0lgSHP3iqW24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}