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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19cb50395485e00929398af12bf8f8f70823fd28a4134383ef90b979aecf715' 
  AND token = 'WGUdXu+IgjGgSc4yEDp/P7571rDjhcsQsfv/vJ3k4dY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}