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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13f5153513eaf9bc47b1ed02ef15981e0ff81d76befba25e2063d79615afe7f5' 
  AND token = 'JjoL8ONNGcQDVh9+CnHB6KDgW7M+v+EkNbswc4NbTAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}