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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc667cc5231b222816bf39070101e7fc32757d31b3951edf300858e3159e3bf8' 
  AND token = 'ttZD/0xQ3d5772BwEpFWnOiUQUgVzv5wMAjsHw2ExBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}