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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341ecadd62b9658c734f20b99f3bf8083cd2597e6b2bebf1e5a4bdd988f21d71' 
  AND token = 'XLtyMWf1hy0OhB4sHh3TKWZE2ICKfwapBQRUVYkTRfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}