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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3870a1b765c3aa923cbac15e2ded0ef7ebcc282627e5bd7eb180fe3bfc666d' 
  AND token = 'jgnPKFgXo0ixt4pAzd2tPXYdrxjt8/XESS40NzVblDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}