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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d75256a0647a946913bb004dae7b606517a7514c6f8086310cc46ee766d26c2' 
  AND token = 'HNTX+rMd5m6xX4UdFm0GV7RhCRQVmPMQwy78k04U/N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}