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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d472ce6a8f1ff0845d3f89c6791291f71b5499d22f92fe1639538dcaf2ddb9' 
  AND token = '/tW1HWTehzkiPCsXtagT2sMkYV8JZk0Q5TGvfaJ/v1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}