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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5f5808e3764c9a0ee5f935dbbd02866f33c66b0f839e92fa7cddb470284503' 
  AND token = 'k1WTM1Ccq5KamKr4MI+0zuKJLnW06igT3TKZd4urZZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}