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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147df0d08366d0353bc0cf6052a69b9fd149155a63086606120b6b9f6cda57d0' 
  AND token = 'JfFls8CPV7QsdA2RK9ZFTBR/YMi7yYNj9GUgESTT1r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}