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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2315e1aca79f27a15d8ee7d5aa6ef22c2a79e5f05ae1669fc180f1418c0a9375' 
  AND token = '7Y5f6zjd6zp6ZD7rRvX3kmc+U7n9QsjGl2aUdHq+vdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}