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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd4d29fbd40c960186463d9d964334ba72d0501c585dfadf30d3d1c22d72373' 
  AND token = 'MDt3lQfWobB/bZkC58994BzD2+NW71+vxzztW6RvckM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}