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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae00e1b57386cecb63d867c9b4b6292b213197d7c192820b3f4f30b5a7282998' 
  AND token = 'xgLo7fY4oIHYoytnv35284eDYLOmENc47L352qy1bQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}