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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5b69b0e704a039efe9919815309012b4ce531b8cfec12008ab2c5fcb069ff5' 
  AND token = 'JoC6M3OmPB9D+YRhXMSXwOA0fZ5hkJElZnL4K8JXTE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}