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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153d875e80bd9dd2354c7d4990abef5373377c1fb1c522d9010e9e03c32cfd7b' 
  AND token = 'J+TH21MypW8Uibngz4IqsBVqAVv3F2EhVqlfTdBo15M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}