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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33aaf2474b328b03ff8bd710d1dc6decd1f239a17ace2ff920016607501a9c01' 
  AND token = 'mt38Hdcj+KtSIE5z0OwuJECJ1DQVcMhRO7p+HnaVIjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}