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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d76961d23f42de29e8f19953e812f84558eff8d75df3a35ea3ec2ecbdde978' 
  AND token = 'QYgTzVBb4ULZ1swYUxSmGYqMO+sc3M5Q1C1ZFp1Sr78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}