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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975a7f043594e76062377f26b8a730fe4801f83659f1f7abab351136af5f294c' 
  AND token = 'I/gKcNr3+5vaX07w1Wh0jiIOMcQkCzo7vs+rr5b2e1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}