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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1f660f7ab27f5dfa3a107a054de6eec97e41779a92832452f0457e20f15750c' 
  AND token = 'J/mjSCm1EYzbiF2wglLQ82t4S1xphEsSr2UcC8fq58k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}