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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453f5fca7149493e4adc470ea3056309d99d566ff49cdc9b65b8328d1bc8af83' 
  AND token = '1vpmpAAQlrcdQ2woWLKeAL94g1m8KuUb7mM4AGlE0wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}