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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4748c4d25fadf53236168a9a3699149d82d49c73ba902abb08634440b25b9168' 
  AND token = 'ALZZNRLk9s+D6QVE+HqLbek7oz2NVDgkXNn4qshRwh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}