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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a393f868834d26ca62bcb936c43795cf31d92b13f98995f431bf5cd9a22edd1c' 
  AND token = 'Yp6PMRu+uTAAtPTQg5gaAQYPjLt56FagXMCPwg3fqo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}