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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859ef763f30ff68072a63830a3bc5c6fa2a17f183b7db89558d102d4dc0ab304' 
  AND token = 'xkl63KC3KVlJPNWNryupd2yf39fJkVOlh4vYniW6c6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}