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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6146fdb350b18b7ee70207e93f4493a7c42b5a4aa6c1a59c278c67e2b1dcb8e5' 
  AND token = 'yTgTm0lFrvzJLAXP+RhHwYGjAI6f7AkdHf3Dhe0TW8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}