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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2dd530f86e4e946dbd7ab547920030429e7ffa5fa883901298480682c15c16' 
  AND token = '8cJH9uVdyLCd6h+3WzDXJ5SF4zfRIrGTMRUg8BfLb7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}