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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8611e01cb6706b7bfca730e43a0c371e7f7404a217ed43435bd19fe1bbc3d7a' 
  AND token = 'kn8aMU1Y7gZ8HEX4fIIe6fz18p/dZQPgCAHfPs9qMLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}