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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be56ae1deb16ac60b4a86bf83ece7cbd0cb2a3891b4c1bb172b88ffafcd5b219' 
  AND token = 'tyHW5B5kXxK0QAZ1DOf/jb265G6QhjDPdUKKzOrzxgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}